Mitochondrial Dysfunction
The known cause of Parkinson’s disease is reduced level of dopamine production by neurons in the brain but surprisingly the main cause was malfunctioning of cell organelles like mitochondria leads to increased oxidative stress which in turn results in cell death and finally ends with Parkinson’s disease with motor and non-motor symptoms. The reason may be both genetic and environment factors.
- Mitophagy
- PARKIN (PARK2)
- KH176
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