Pathophysiology and Pharmacology


Parkinson’s disease is originated because of the gradual loss of cells in the substantia nigra of the brain. Dopamine is a neurotransmitter that transmits signals between two regions of the brain to coordinate activities like movement of limbs. If there is deficiency in dopamine production results in loss of co-ordination and end up with symptoms of Parkinson’s disease. As the disease progresses, nervous system and brain degenerates causing a higher movement disorder.



 


  • Levodopa
  • Bromocriptine
  • Brain Cell Death

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